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This narrative review aims to synthesise the current evidence on the most frequently proposed management strategies for this patient subset ( Figure 1 ), critically examining their pathophysiological underpinnings and clinical efficacy

An even lower TUL for iodine has been proposed by the American Thyroid Association (ATA), that advises against exceeding 500 g per day of iodine, particularly in children, the elderly and during pregnancy [22]

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Additionally, the dosage and duration of supplementation play critical roles in determining the extent of skin-lightening effects