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Hai Wen (Shanghai Changzheng Hospital, Second Military Medical University) for his assistance in the design of this case report

2019 [cited 2019 Jun 9]

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It acts on adipocytes to enhance the hydrolysis of stored triglycerides without globally activating growth hormone cascades

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On the other hand, double Ghr ko/ Igf1 ko resulted in further postnatal growth retardation relative to Igf1 ko mice completely obstructing further weight gain after postnatal day 15 and supporting previous studies suggesting that progenitor cells in the growth plate require direct GH actions (24)