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Most antioxidant enzymes contain redox-sensitive gene regulatory sequences in their promoter and/or intron regions that can interact with transcription factors to trigger upregulation of gene expression (13)

In PCOS, where OS, androgen excess, and IR coalesce, melatonin re-establishes a synchronized endocrine rhythm, offering both mechanistic and therapeutic promise as part of a redox-endocrine restoration strategy

Furthermore, scientists have suggested it may also improve energy expenditure, giving it therapeutic potential for treating individuals with obesity or metabolic disorders

Because these supplements have some overlapping effects, its important to speak with your doctor before taking the two together

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Conversely, the group receiving TIR did not demonstrate any significant differences from the control group