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These values are several orders of magnitude higher than those in the human body

Low to intermediate levels of ROS and RNS are necessary for the maintenance of many important physiological functions, redox homeostasis, and the regulation of key transcription factors

TrkB neurotrophic activities are blocked by alpha-synuclein, triggering dopaminergic cell death in Parkinson's disease

As a result, it induces ferroptosis, a form of non-apoptotic cell death [1]

Contemporary research indicates that neoplastic cells undergoing ferroptosis may also discharge DAMPs into the extracellular milieu through autophagy, thereby enlisting and stimulating immune cells