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Proteome reactivity of BDHI-containing fragments Based on our analysis of fluorescent and biorthogonal BDHI probes, we envisioned that BDHI warheads could be used to produce small molecules capable of selectively reacting with distinct subsets of the human proteome

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Ailanthone, a novel inhibitor targeting transcription factor c-Jun, downregulates PD-L1 expression in melanoma cells while reducing infiltration of immunosuppressive regulatory T cells (Tregs) in tumors, thereby potentiating anti-PD-L1 antibody therapy (35)

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10.1016/s0140-6736(87)91988-x [DOI] [PubMed] [Google Scholar] 189.Iliev ID, Leonardi I

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King et al., 2019)

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21 Belman was the pioneer to reveal chemopreventive effects of garlic oil against skin tumorigenesis initiated by DMBA and promoted by PMA

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GO enrichment analysis and GSEA showed that ATF4 was closely related to autophagy and the mTORC1 pathway, respectively ( Figure 8 )

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