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For glucose metabolism, a common consequence is to induce preferentially utilization of glucose through glycolysis rather than tricarboxylic acid (TCA) cycle (referred as Warburg effect) under aerobic conditions [5, 6]

L., Holliday D

E., Ross M

Methods Ethics statement All experimental procedures involving mice were reviewed and approved by the Columbia University Institutional Animal Care and Use Committee (IACUC)

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Whether this enhanced potency is due to the heterodimerization of the receptors is still unknown