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However, the subsequent reperfusion, meant to restore normal blood flow, exacerbates the damage through the formation of reactive oxygen species (ROS), inflammatory mediators, and the activation of numerous signaling pathways (Snchez-Hernndez et al., 2020)

J Pharm Pharmacol (2013) 65:103743

Perrino T, Beardslee W, Bernal G, et al

Wilkins HM, Marquardt K, Lash LH, Linseman DA: Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione