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The plasma sample, along with a spiked internal reference standard (synthetic long-R3-IGF-1 (LR3)), was incubated for 30 minutes

In a case report, it was found that the patients behavioral problems improved in the first month of a 16-month ketogenic diet intervention in a six-year-old child with ASD symptoms, and 18 FDG PET decreased significantly in 12 months [48]

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When assessing in more detail the response dynamics of the genes affected at all three time points, 5 and 29 genes showed a continuous increase in down- and up-regulation from early to late time points (i.e