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Lysosomal instability and release of lysosomal content into the cytosol have been proposed as a mechanism by which lysosomes can contribute to APAP-induced hepatotoxicity

This syndrome, which is aggravated by selenium shortage, is often seen in patients who are in critical condition

10.1016/j.isci.2024.109737 84 PontelL

Laptenko, O., Tong, D

Ghosh AK, Mau T, O'Brien M, Garg S, Yung R

However, it is likely that dysregulation of the cytokine homeostasis in inflame-aging phenomenon may play a critical role in the risk of a cytokine storm, and subsequently acute respiratory distress syndrome (ARDS) in some elderly patients with severe COVID-19 infection