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doi: 10.3390/nu11020353 184 RuheeRTMaSSuzukiK

Then, 2 l of each reaction was transferred to 18 l quenching buffer (500 mM EDTA pH 8.0) at 0, 3, 6, 9, 12, and 15 min

The mechanisms behind that repair, however, are not interchangeable

Sh-Oligopeptide-1 is the famous molecule, which is also called Epidermal Growth Factor or EGF

Specific ion effects at the air/water interface

What they found: 4,192 human genes change expression by 2 in response to GHK-Cu (31.2 % of the human genome) Of these 2,296 genes up-regulated , 1,896 down-regulated Pattern of changes: a rejuvenating signature, genes typically associated with ageing are down-regulated, regenerative genes up-regulated DNA repair , strong up-regulation of genes in BER, HR, NER pathways Mitochondrial biogenesis , increase in the number of mitochondria in cells Anti-apoptotic signal , protection against cell death Down-regulation of cancer signals , some oncogenes decreased Why it matters: This is the strongest evidence for the pleiotropic nature of GHK-Cu