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Fanelli S, Francioso A, Cavallaro R, et al

TGA named BPC157, GHKCu, TB500, retatrutide, and CJC1295 as examples of unapproved peptides

Two studies involved intravenous injection, and four studies involved an oral tablet

Commonly Reported Side Effects Most of the side effects described online are mild and include: Injection-site redness or irritation Bruising Headache Nausea Temporary fatigue These reports are largely anecdotal and should not be treated as definitive safety data

This makes targeting the Nrf2GPX4 pathway a highly promising and important direction for developing OA disease-modifying therapies (Figure 1)

Ongoing Research: The potential health benefits of ergothioneine treatment are numerous and exciting