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Adoptive cell therapies such as CAR T and NK cells face major challenges within the oxidative TME

56 Other Opioid Agonist Treatments Other full agonist opioids may be options for OUD treatment initiation and maintenance in the fentanyl era

Ali-Osman F, Akande O, Antoun G, Mao JX, Buolamwini J

9.9 Limitations of clinical implementations Preclinical testing of multi-target therapies poses additional challenges, as current animal models and testing protocols often do not accurately capture the complex interactions of multiple targets (256)