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Folinic acid treatment for schizophrenia associated with folate receptor autoantibodies

pain, viral illness) or ingest therapeutic doses of paracetamol and have symptoms of acute liver injury (e.g

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However, the contribution of Prdx6 to the reduction of phospholipid hydroperoxides is overall outperformed by other proteins, in particular GSH peroxidase 4 (GPX4), which was the first enzyme with this activity described in the literature, having exceptionally high second-order rate constants for phospholipid hydroperoxide reduction (~10 6 10 8 M 1 s 1 ) compared to Prdx6 (~10 4 10 5 M 1 s 1 ) [26, 38, 39]