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The aging process affects the stomachs ability to produce intrinsic factor, a protein necessary for B12 absorption, explains why older adults need regular shots

It aids in managing weakness and fatigue

Prolonged exposure to estradiol also created a new homeostatic status in which immune cells were potentiated and ECs were less sensible to pro-inflammatory stimuli and apoptosis (Figure 2) (109)

B12 injections can help

Diagnosis relies on B12 levels, methylmalonic acid, homocysteine, and intrinsic-factor antibodies interpreted by a clinician

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