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Adhesive capsulitis, or frozen shoulder, can be a consequence of a specific injury or it can be linked to diseases like diabetes, or hypothyroidism

Genes involved in early onset glaucoma have been identified by large-family linkage analysis, whereas genes involved in adult-onset disease have been identified by genome-wide association studies (GWAS), usually requiring a large number of glaucoma cases and controls (Wiggs, 2015

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(II) The gamma-glutamylcysteine synthetase enzyme is the main rate-limiting step in this cycle, and this reaction is non-allosterically inhibited by physiologic concentrations of glutathione

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These carriers can be engineered for surface modification with ligands targeting dopaminergic neurons or inflamed brain regions, enabling precision delivery and minimizing off-target toxicity (Naqvi et al., 2020