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Mutations in SLY1 can disrupt GA signaling, offering a potential strategy to enhance drought tolerance by modulating growth responses

Tsoukalas D, Fragkiadaki P, Docea AO, et al

In summary, MOTS-c powerfully supports muscle metabolism by improving insulin sensitivity, boosting glucose and fatty acid utilization, and even mimicking some effects of endurance exercise a profile that is highly promising for addressing metabolic health and age-related muscle decline

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Although the relevance of the present study to the human disease deserves further investigation, these findings may be useful to future studies using this model of colitis aimed to understand the pathophysiology of IBD

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