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This stability supports its use across biochemical, cellular and preclinical experimental platforms

doi: 10.1038/s41420-018-0119-5

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In the CNS, they participate in increasing neuronal excitability and promote synaptic plasticity, which are key for learning and memory, through second messenger signaling pathways ( Figure 1 ) according to their pharmacology, sequence of amino acid homology, and signal transduction pathways ( 2+ from intracellular stores in the endoplasmic reticulum, and diacylglycerol activates protein kinase C ( + channels and inhibit voltage-gated Ca 2+ channels ( Figure 1