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Increased glucose partitioning to serine following SAAR is abolished by loss of hepatic PSAT1 Next, we aimed to further connect the attenuated improvement in glucose tolerance observed in liver PSAT1 KO mice fed a HF-SAAR diet to inability of hepatocytes to synthesize serine from glucose (Fig

Lee HY, Choi YP, Kim S, Yoon T, Guo Z, Lee S et al

Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B 12 metabolism

However, the pentose phosphate pathway can also return metabolites to glycolysis, because fructose-6-phosphate and glyceraldehyde-3-phosphate are also formed in the non-oxidative phase

This protection from inflated inflammation and immune responses is achieved by augmenting the innate immune mechanism and enhancing neutrophil and natural killer cell activities