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Trends Pharmacol Sci 30 , 515527, doi:S0165-6147(09)00128-X 10.1016/j.tips.2009.07.006 (2009)

These viral proteins act as multifaceted devices that re-program host cell functions at multiple levels, weakening the normally tight links between cellular differentiation and proliferation

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In the context of trichology and dermatology, it is often referred to as a "signal peptide" because it communicates with cells to stimulate repair and regeneration