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These three basic mechanisms (oxidative stress, chronic inflammation, and endothelial dysfunction) play very important key roles

This study highlights an effective strategy for investigating the holistic PK of complex macromolecular components and provides valuable data on the bioavailability of polysaccharides in TCM

This dilemma can be solved by introducing bioactive substances, such as heparin, into the wound dressing and the mutual attraction between its sulfate group and the positively charged amino acid residue of inflammatory factors, thus capturing inflammatory factors [146, 158]

2.3 Lipid peroxide accumulation Polyunsaturated fatty acids (PUFAs), which are major constituents of organelle membrane phospholipids, are particularly prone to peroxidation during ferroptosis (Han et al., 2025)

Because of their capacity to recapitulate the major structural and functional characteristics of epithelium in vivo, enteroids are widely used in studies of cancer, gastrointestinal infection, and drug development (Zou et al., 2019

Ideally some of the cysteine is eventually converted to sulfate which is used as a conjugate for sulphation, a vital phase 2 detoxification pathway that handles many different toxins including excess oestrogen