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Studies using rat models with transected Achilles tendons showed BPC-157 treatment resulted in accelerated recovery with increased load to failure, superior Achilles Functional Index scores, enhanced mononuclear cell infiltration, improved collagen fiber organization, and smaller persistent defects compared to untreated controls

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Notably, Selenoprotein H (SELH) and Interleukin 33 (IL33) belonged to the most downregulated proteins and using immuno-based approaches, we confirmed loss of intracellular SELH using ELISA and loss of IL33 using Western Blot analysis (Supplemental Fig

One of the authors has significant statistical expertise