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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Huang X., Atwood C

Furrie, 2006), promoting an anti-inflammatory environment through modulation of host immune response (Lopez et al., 2011), production of vitamins and short chain fatty acids, digestion of plant oligo- and poly-saccharides, and suppressing the production of potentially toxic and carcinogenic metabolites (Sela et al., 2008)

Microbiota-derived metabolites are key mediators of host-microbe interactions ( 2.3 Bidirectional neuroendocrine crosstalk In addition to regulating host metabolism and immune responses, the gut microbiota is recognized to play a critical role in the production of neurotransmitters and engages in complex bidirectional communication with the hypothalamicpituitarygonadal (HPG) axis, contributing significantly to the pathogenesis and potential treatment of PCOS

EMBO Jour 33(9):939941