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CJC-1295 stimulates the release of growth hormone-releasing hormone (GHRH), while Ipamorelin acts as a growth hormone secretagogue, promoting GH production

Jhelum P, Santos-Nogueira E, Teo W, Haumont A, Lenol I, Stys PK, et al

Critically, this mechanism is selective for senescent cells because non-senescent cells do not accumulate FOXO4 in PML bodies and do not depend on FOXO4-p53 sequestration for survival