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Journal of Materials Chemistry B

Disclosures: John Suschak: Altimmune: Employee, Maynara Lucca Andrade: Altimmune Inc: Employee, Bertrand Georges: Nothing to Disclose, Sarah Browne: Nothing to Disclose, Christina Alonso: Nothing to Disclose, Scott Harris: Altimmune: Employee, Scot Roberts: Altimmune: Executive role 629 SINGLE-CELL IMAGING MASS CYTOMETRY DEFINES IMMUNE CELL COMPOSITION AND SPATIAL INTERACTIONS WITH APOPTOTIC HEPATOCYTES IN IMMUNE-MEDIATED LIVER INJURY FROM CHECKPOINT INHIBITORS (ILICI) AND AUTOIMMUNE HEPATITIS (AIH) Jacob Bogdanov 1 Neil Zhao 2 Layla Shojaie 1 Helia Alavifard 1 Mahmoud Mohamed 1 Aria Baktash 1 Andrew Stolz 1 Akil Merchant 3 David Kleiner 4 Robert Fontana 2 Jonathan Sexton 2 Lily Dara 1 , 1 University of Southern California, 2 University of Michigan, 3 Cedars-Sinai Medical Center, 4 National Cancer Institute, Bethesda Background: Rising use of immune checkpoint inhibitors (ICI) targeting the Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1) pathways has transformed oncology

Following incubation, cells were rinsed in PBS then incubated with WST-1 reagent (diluted 1:10 into fresh starved media (Roche, UK)) and incubated at 37 C for 4 h in a cell culture incubator according to manufacturers instructions

Improves skin elasticity and firmness

This will open up new paths for treating IBD symptoms

Researchers found that skin treated with the 2% KYOWA oxidized glutathione location had significant whitening over the placebo group, said Ryusuke Nakagiri, Senior Director of Strategic Science at Kyowa Hakko USA