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Zhangs study demonstrated that the synthesis of GSH is intricately linked to serine metabolism, with its metabolic byproducts lactate and 2-hydroxyglutarate (2-HG) suppressing the cytotoxic function of T cells

524,525 This state of chronic, low-grade inflammation is strongly associated with various diseases and pathologies, including arteriosclerosis, neuroinflammation, osteoarthritis, and intervertebral disc degeneration

The qualitative shift suggests specific molecular mechanisms that remain to be elucidated

We discuss how microbes in our gut impact our mental and physical health and how diet and the environment affect the gut microbiome

Structure and expression of glutathione S-transferase genes from the midgut of the common cutworm, Spodoptera litura (Noctuidae) and their response to xenobiotic compounds and bacteria

10.1016/j.biomaterials.2014.06.040 186 YamanishiY.BoyleD