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Moreover, this metabolic shift from glycolysis to FAO in senescent ECs is closely associated with increased secretion of proinflammatory factors characteristic of the senescence-associated secretory phenotype (SASP), which exacerbates chronic vascular inflammation (often referred to as inflammaging) and contributes to vascular diseases such as atherosclerosis and hypertension [105]

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

102.Viswanathan VS et al

Information about the predisposition of various diseases due to genetic variants has been evaluated

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