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The analysis of EV cargo offers potential for targeted therapeutic interventions, providing valuable insights into the inflammatory response involved in CF lung disease

Berk BC Transactions of the American Clinical and Climatological Association

10.1111/j.1365-313X.2007.03280.x 29 MeyerA

Above all, mast cells are central drivers that release mediators such as IL-6 and CXCL10 in response to estrogen deficiency, which impairs bone repair and promotes vascular inflammation (83, 84)

Furthermore, combination metformin and 1.8 Gy radiation treatment significantly increased the percentage of early apoptotic HCT116 cells, when compared to irradiated vehicle control ( Figure 3B )