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Results: Evidence indicates local estrogen dominance with progesterone resistance, pervasive immune dysregulation, and oxidative stress with iron-driven ferroptosis that particularly injures granulosa cells, alongside disease-relevant genetic/epigenetic regulators and reproductive-tract/gut microbiome dysbiosis

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PMID 16189514

Use only sterile water (0.9% sodium chloride with 0.9% benzyl alcohol) for mixing, as this provides antimicrobial preservation and keeps isotonicity

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