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The Golgi also serves as a transient zinc reservoir, regulating dynamic flux between the cytosol and secretory pathway

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The current study aims to elucidate the potential benefits of SIT in mitigating PTX-provoked testicular damage in rats by mediating oxidative stress, ER stress, inflammation, and apoptosis pathways

These drugs induce apoptosis inhibition by forming a complex with the intracellular immunophilin FKBP12 thus inhibiting the phosphorylation of the mTOR targets, S6K1 and 4E-BP1, as a result, the activation of cyclin-dependent kinases (CDK) is prevented, specifically, the expression of cyclin D1 is found to be decreased meanwhile p27 increases and consequently, cells arrested at G1/S phase die either by autophagy or apoptosis (197, 198)

Mangosteen Known as the queen of fruits, mangosteen contains xanthones antioxidants that protect the liver and lungs