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"FDA Response to three Citizen Petitions against biosimilars" (PDF), FDA , 30 May 2006, archived from the original (PDF) on June 19, 2006, retrieved 23 November 2015 In 2023, the FDA approved a different sustained-release form of growth hormone, Sogroya (somapacitan-beco) (Novo) for both pediatric patients (2.5 years and older) and adult patients, whom have growth failure due to inadequate secretion of endogenous growth hormone (rHGH)

High-concentration mAb formulations frequently contain excipients such as salts or amino acids to modify or weaken protein-protein interactions, thereby lowering the viscosity while maintaining colloidal stability

At room temperature and physiological pH, unmodified small peptides in solution degrade over days to weeks, not months

PMID: 31300053

These compounds work differently inside our bodies

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