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Additionally, glycine degradation occurs via the glycine cleavage system (GCS), a mitochondrial enzyme complex predominantly found in astrocytes, which regulates glycine homeostasis and metabolic fluxes in the CNS (Aprison 1990

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Despite this, these cells have a relatively long lifespan of approximately 120 days in the bloodstream [9]

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58,59 demonstrated that downregulation of IFN-sensitive gene expression by interference with STAT-1 methylation can promote interaction with the protein inhibitor of activated STATs (PIAS)

Multiple sclerosis deep grey matter: The relation between demyelination, neurodegeneration, inflammation and iron