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Abbreviations HIF: Hypoxia inducible factor GSH: Glutathione Ac-LDL: Acetylated low-density lipoprotein GSEA: Gene set enrichment analysis DE: Differentially expressed (genes) References Meir JU, Champagne CD, Costa DP, Williams CL, Ponganis PJ

Luks and Hackett, 2022)

Plasma amino acid concentrations were determined by ion exchange HPLC

Atherosclerosis 269, 306311

Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation

For instance, isobaric metabolites or structural isomers cannot readily be differentiated from each other solely based on the beforementioned physicochemical parameters due to (i) co-elution, (ii) similar MS, or (iii) MS2 spectral data