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FIGURE 3 To verify that these phenomena were indeed caused by GPX4 activation, we tested the effects of compound 102 on other seven enzymes in the AA network, including COX-1, COX-2, mPGES-1, 5-LOX, LTA 4 H, 12-LOX, and 15-LOX

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Studies in vitro have shown that it can reduce levels of pro-inflammatory cytokines such as TNF- and the p-NFB marker, highlighting an overall anti-inflammatory effect

For example, fatty acids (e.g., stearic acid) detected in the infective stages of helminths are known to have a role in host interaction through facilitating successful penetration and migration inside the host