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Statistical analyses were performed with SPSS version 13.0 software (SPSS, Inc., Chicago, IL)

Finally, the upper layer was analyzed using the LC-MS/MS system

Specifically, our study has shown that the superoxide level within the mitochondria was reduced by exogenous METTL7A, indicating an ameliorated mitochondria stress in cleavage embryos, which was further supported by observations of overall lower mitochondrial activities and down- regulation of HIF-1

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