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doi: 10.1002/cncr.32802 2 JiaMZhengRZhangSZengHZouXChenW

J Assist Reprod Genet (2016) 33:136372

Moreover, dysregulated lipid metabolism networks such as ACSL/SCD also drive EMT and migratory properties, and their pharmacologic inhibition selectively impairs CRC cell viability, further broadening the landscape of metabolic vulnerabilities in metastatic CRC [96]