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In its initial human clinical trial, fenugreek extract was deemed safe and well-tolerated (546)

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Osteogenesis and osteogenesis stimulated by LPS were confirmed by RT-PCR of osteogenesis-related genes ALP (alkaline phosphatase), RUNX2 (Runt-related transcription factor 2), OCN (osteocalcina), and OSX (osterix) ( in vitro and also blocked the induction of osteogenesis-related genes, emphasizing its major role in osteogenesis ( in vitro , in the presence or absence of LPS

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Routes are primarily subcutaneous or intravenous, and timing spans from single pre-activity doses to daily regimens

Immune system to brain signaling: Neuropsychopharmacological implications