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Description

HK-2 cells The cell line HK-2 was purchased from the American Type Culture Collection (ATCC, Manassas, VA, USA)

The RDA for vitamin B12 is 2.4 mcg for men and women over 14 years old

Devices 15, 107117

Activated by lipotoxicity and ER stress signals, NLRP3 triggers IL-1 and IL-18 release specifically in adipocytes, promoting tissue inflammation and macrophage recruitment (103, 104)