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This comprehensive approach makes GHK-Cu valuable for research applications requiring broad cellular support rather than single-target interventions

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This decrease was more pronounced when adipocytes from HSL-null mice were utilized, a finding that suggests cooperativity exists between the two enzymes, and indeed, a synergistic effect has been observed on lipolysis when cells are cotransfected with both desnutrin/ATGL and HSL (144)

The copper delivery hypothesis proposes that GHK-Cu regulates intracellular copper levels, which in turn affect copper-dependent transcription factors and enzymes