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Accutane may reduce fertility and increase miscarriage risk in women

Hyperammonaemia triggers numerous neurological and neuropsychiatric symptoms, including poor concentration, impaired memory and cognition, psychotic presentations, sleep disturbance and lethargy, and stupor and coma in severe cases

The excessive accumulation of copper not only exacerbates immune responses through these direct oxidative damage pathways but may also influence immune cell function by altering the metal ion balance in immune cells, thus advancing neurodegenerative processes (131)

Its abnormal activation not only affects immune system function but also participates in the damage process of important organs such as the lungs and heart, suggesting that targeted regulation of the mTOR pathway may be a new therapeutic strategy for multi-organ protection in sepsis

Del Rey MQ, Mancias JD

Neurological disorders and mitochondria