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Bayona-Bafaluy, M

Over time, due to DNA replication and oxidative stress, telomeres shorten

Likewise, methods used to assess mtDNA mutations and deletionsincluding long-range PCR, NGS, and targeted mitochondrial arraysvary widely in their ability to detect low heteroplasmy or large structural variants (131133)

6 Discussion Synthesizing the foregoing evidence, this article proposes a central hypothesis of ferroptosis in periodontitis: ferroptosis is not merely a passive accompaniment to disease progression, but has the potential to evolve into an important node and signal amplification link within the pathological network

The role of zinc is not universally beneficial

The alteration method involves a coating of the surface with a biological bonding agent, non-ionic surfactant and specific cell or antibodies or by albumin protein