ALT is a component in the alanineglucose cycle converting pyruvate to alanine in muscle, and alanine back to pyruvate to make glucose in the liver
This work finds that an embryonic survival phenotype (diapause) is co-opted by cancer cells to promote survival during drug treatment
10.1016/j.bioactmat.2023.01.010 24 ChenX.JingS.XueC.GuanX
J Clin Invest 127(10):36093623 Mahrooz A, Muscogiuri G, Buzzetti R et al (2021) The complex combination of COVID-19 and diabetes: pleiotropic changes in glucose metabolism
The annual medical expenditure for DED in the United States is approximately $ 3.8 billion, imposing a huge economic burden on society [2]
Louandre C, Marcq I, Bouhlal H, Chauffert A et al (2015) The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells