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The median ages of the patients treated with eltrombopag and placebo were 47 years and 52.5 years, respectively

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Marx et al., 2011a

In the initial phase (1.55 M), it activates peroxisome proliferator-activated receptor (PPAR) receptors and inhibits toll-like receptor 4/myeloid differentiation primary response 88 (TLR4/MyD88) complex formation, blocking inhibitor of nuclear factor kappa-B kinase subunit (IKK) phosphorylation (IC50 = 5.2 M)

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