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For longer term storage, freezing at -20C is recommended to maintain integrity

Prominent cases of neurodegenerative illnesses include Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, frontotemporal dementia, and spinocerebellar ataxias

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You might expect to see some initial brightening by the 4th or 5th week of regular IV therapy