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[1] This leads to better hydration, and with enough glycerol and water (you'd want to keep drinking more than what's in the 12 ounce bottle), leads to a "hyperhydration" effect

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However, many people cannot accept the undesired side effects of these drugs such as gastric hemorrhage, perforation of gastric ulcers, and cardiovascular disease [8]

Drugs Exp Clin Res 1992;18:355-65

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Empirical evidence for definitions of episode, remission, recovery, relapse and recurrence in depression: a systematic review