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In sepsis-associated encephalopathy, mitochondrial dysfunction occurs in the setting of systemic inflammation, which contributes to increased blood-brain barrier permeability and resultant neuroinflammation [15, 16]

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This method of utilizing disease-specific interactions presents an appreciable advancement in specificity and relevance (66)

Ferroptosis affects not only the microvasculature but also RPE cells

Plant genomes though said to have evolved dynamically but have been observed to maintain conserved universal domain architectures 43