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Absorption through the gut depends on a protein called intrinsic factor, production of which declines with age, certain medications (notably metformin and proton-pump inhibitors), and conditions such as atrophic gastritis

doi: 10.3390/genes15010031 120 LamonicaJMKwonDYGoffinDFenikPJohnsonBSCuiYet al

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Thus, it can be noted that the content of this element in soil and food grown in these areas may be very low

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We speculated that the change in behavior was related to impairment of synaptic transmission resulting from alcohol-induced oxidative damage and mitochondrial energy depletion, leading to loss of neuronal activity