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However, more recent studies evaluating CD loci showed a possible role of other genes involved in barrier functions and cell-cell adhesion (272274)

A simple way to picture it is friction

Effects of Tesamorelin in HIV-infected individuals with excess abdominal fat

and Tosti, A., 2021

Anxiety can deepen the same loop, since excessive worry often brings muscle tension, restlessness, and trouble concentrating, symptoms detailed by the Mayo Clinic in its guide to generalized anxiety disorder

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