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The three most common types of hyperpigmentation include: Melasma: Often caused by hormonal fluctuations during pregnancy or birth control use, melasma appears as dark, irregular patches, usually on the face

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In this group of patients, malignancies of the thyroid gland appear as early as 5 years after radiation therapy and may appear 20 or more years later.[5] Radiation exposure as a consequence of nuclear fallout has also been associated with a high risk of thyroid cancer, especially in children.[6-8] Other risk factors for thyroid cancer include:[9] Diagnostic and Staging Evaluation The following tests and procedures may be used in the diagnosis and staging of thyroid cancer: Physical examination and history