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Carrion Crow Bayou (November 11, 1863)

After the proposal of cancer chemoprevention, several agents were successfully approved by FDA for cancer prevention (Table 1)

To note, the middle product NIR-PZ was synthesized from IR820 and piperazine and then reacted with 4-chloro-7-nitrobenzofurazan to afford the probe NIR-H 2 S through the nucleophilic substitution reaction