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Description

The approach of targeting senescence is known as senotherapy, which mainly includes senolytics, senomorphics, and rejuvenating agents (Table 2

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Effective inhibition of c-Met, p-AKT, and p-ERK was achieved by dual inhibition with the BRAF inhibitor (PLX4032) and c-Met inhibitor (PHA665752)

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Potential Benefits Wound healing (preclinical): Animal studies report faster wound healing and tissue repair via enhanced angiogenesis and cell migration [5] [6]

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Juvenile models are particularly susceptible to these CNS changes during treatment

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